Publications

2020
[132] I. Zoi, Antoniou, D., and Schwartz, S. D., “

Linking protein dynamics to enzyme catalysis

”, in Comprehensive Natural Products III (Chemistry and Biology), vol. 4, Elsevier, 2020, pp. 578-587. compreh_nat_prod_2020.pdf
[130] J. Schafer and Schwartz, S. D., “

Directed evolution's influence on rapid density fluctuations illustrates how protein dynamics can become coupled to chemistry

”, ACS Catalysis, vol. 10, pp. -8476-8484, 2020. acscatal_10_8476_2020.pdf acscatal_10_8476_2020_si.pdf
2018
[124] R. Harijan, Zoi, I., Antoniou, D., Schwartz, S. D., and Schramm, V. L., “

Inverse enzyme isotope effects in human purine nucleoside phosphorylase with heavy asparagine labels

”, Proc. Natl. Acad. Sci. USA, vol. 115, pp. 2609-2616, 2018. pnas_115_e6209_2018.pdf pnas_115_e6209_2018_si.pdf
[121] V. L. Schramm and Schwartz, S. D., “

Promoting vibrations and the function of enzymes. Emerging theoretical and experimental convergence

”, Biochemistry, vol. 57, pp. 3299-3308, 2018. biochem_57_3299_2018.pdf
[120] X. Chen and Schwartz, S. D., “

Directed evolution as a probe of rate promoting vibrations introduced via mutational change

”, Biochemistry, vol. 57, pp. 3289-3298, 2018. biochem_57_3289_2018.pdf
2017
[115] I. Zoi, Antoniou, D., and Schwartz, S. D., “

Incorporating fast protein dynamics into enzyme design: a proposed mutant aromatic amine dehydrogenase

”, J. Phys. Chem. B, vol. 121, pp. 7290-7298, 2017. jpcb_121_7290_2017.pdf jpcb_121_7290_2017_si.pdf
[113] R. Harijan, Zoi, I., Antoniou, D., Schwartz, S. D., and Schramm, V. L., “

Catalytic-site design for inverse heavy-enzyme isotope effects in human PNP

”, Proc. Natl. Acad. Sci. USA, vol. 114, pp. 6456-6461, 2017. pnas_114_6456_2017.pdf pnas_114_6456_2017_si.pdf
2016
[105] I. Zoi, Suarez, J., Antoniou, D., Cameron, S., Schramm, V. L., and Schwartz, S. D., “

Modulating enzyme catalysis through mutations designed to alter rapid protein dynamics

”, J. Am. Chem. Soc., vol. 138, pp. 3403-3409, 2016. jacs_138_3403_2016.pdf jacs_138_3403_2016_si.pdf