Publications

2018
[123] M. Williams, Tardiff, J., and Schwartz, S. D., “

The mechanism of cardiac tropomyosin transitions on filamentous actin as revealed by all atom steered molecular dynamics simulations

”, J. Phys. Chem. Lett., vol. 9, pp. 3301-3306, 2018. jpcl_9_3301_2018.pdf jpcl_9_3301_2018_si.pdf
2017
[114] M. McConnell, Williams, M., Lynn, M., Schwartz, B., Schwartz, S. D., and Tardiff, J., “

Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap

”, Biochemistry, vol. 56, pp. 3403-3413, 2017. biochem_56_3403_2017.pdf biochem_56_3403_2017_si.pdf
2016
[106] M. Williams, Lehman, S., Tardiff, J., and Schwartz, S. D., “

Atomic resolution probe for allostery in the regulatory thin filament

”, Proc. Natl. Acad. Sci. USA, vol. 113, pp. 3257-3262, 2016. pnas_113_3257_2016.pdf pnas_113_3257_2016_si.pdf average_structure.pdb_.zip
2012
[91] E. Manning, Tardiff, J., and Schwartz, S. D., “

Molecular effects of familial hypertrophic cardiopathy-related mutations in the TNT1 domain of cTnT

”, J. Mol. Biol., vol. 421, pp. 54, 2012. jmb_421_54_2012.pdf jmb_421_54_2012_si.pdf
2011
[90] E. Manning, Tardiff, J., and Schwartz, S. D., “

A model of Calcium activation of the cardiac thin filament

”, Biochemistry, vol. 50, pp. 7405, 2011. biochem_50_7405_2011.pdf biochem_50_7405_2011_si.pdf
2007
[70] P. Guinto, Manning, E., Schwartz, S. D., and Tardiff, J., “

Computational characterization of mutations in cardiac troponin T known to cause familial hypertrophic cardiomyopathy

”, J. Theor. Comp. Chem., vol. 6, pp. 413, 2007. jtcc_6_413_2007.pdf
2005
[59] B. Eritz-Berger, Nunez, S., Schwartz, S. D., and Tardiff, J., “

Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice

”, Proc. Natl. Acad. Sci. USA, vol. 102, pp. 18219, 2005. pnas_102_18219_2005.pdf